Glossary

Abbreviations

ACC, American College of Cardiology

ACS, acute coronary syndromes

AHA, America Heart Association

ARC-HBR, Academic Research Consortium for High Bleeding Risk

ASA, acetylsalicylic acid (aspirin)

DAPT, dual antiplatelet therapy

DES, drug-eluting stent

ESC, European Society of Cardiology

NICE, National Institute for Health and Care Excellence

NSTE-ACS, non-ST-segment elevation ACS

PCI, percutaneous coronary intervention

PRECISE-DAPT, PREdicting bleeding Complications In patients undergoing Stent implantation and subsEquent Dual Anti Platelet Therapy

RCT, randomised controlled trial

SCAI, Society for Cardiovascular Angiography & Intervention

Useful definitions

Drug eluting stent: New generation drug-eluting stents.

High bleeding risk: We refer to the definition used by the ESC (an increased risk of spontaneous bleeding during DAPT, e.g. PRECISE-DAPT score ≥25 or ARC-HBR criteria met, as outlined in the following publication: https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.119.040167)

NSTE-ACS: Patients with acute chest discomfort but no persistent ST-segment elevation; on the myocardial level, this may be seen as non-ST-segment elevation myocardial infarction (NSTEMI) or myocardial ischaemia without cell damage (unstable angina)

Bleeding risk tools

ACUITY: http://europepmc.org/article/MED/20513595

ACR-HBR: https://pubmed.ncbi.nlm.nih.gov/32065586/

BleeMACS: https://pubmed.ncbi.nlm.nih.gov/29407077/

CREDO-Kyoto: https://www.ahajournals.org/doi/full/10.1161/JAHA.118.008708

CRUSADE: https://pubmed.ncbi.nlm.nih.gov/19332461/

DAPT score: http://tools.acc.org/daptriskapp/#!/content/calculator/

DUTCH ASA score: https://pubmed.ncbi.nlm.nih.gov/23609946/

PARIS: https://www.sciencedirect.com/science/article/pii/S0735109716015904

PRECISE-DAPT: http://www.precisedaptscore.com/predapt/

REACH: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869443/

Thrombotic risk tools

CREDO-Kyoto: https://www.ahajournals.org/doi/full/10.1161/JAHA.118.008708

GRACE: https://pubmed.ncbi.nlm.nih.gov/23168283/

PARIS: https://www.sciencedirect.com/science/article/pii/S0735109716015904